Liverpool begin their Champions League campaign with a home game against arguably the most difficult opponent in Group E, in Sevilla.
The Spanish side finished fourth in Spain, behind Real Madrid, Barcelona and Atletico Madrid, and overcame Istanbul Basaksehir in the qualifying round to make it this far.
Following an unexpected and harrowing 5-0 defeat at Manchester City on Saturday, Liverpool will be hoping to bounce back when they return to what will be an excited and electric Anfield.
One advantage of having so many more matches this season is that it gives them the chance to put poor performances behind them quickly, and this is one such occasion.
Sevilla played in England a couple of times during pre-season, with little success. They went to Goodison Park and drew 2-2 with Everton, and also lost 2-0 at Southampton.
Loris Karius, whose only appearance so far this season came in the 4-0 win over Arsenal, is expected to be Liverpool’s Champions League goalkeeper and will therefore play in this game, as Jurgen Klopp adopts the Barcelona model of a couple of seasons ago, when they played Claudio Bravo in the league and Marc-Andre Ter Stegen in the cup.
Whilst seemingly being harsh on Simon Mignolet, it is clear that the Belgian is not viewed as Liverpool’s number one goalkeeper, and that Klopp sees fellow German Karius as the better long-term option.
Philippe Coutinho, though, will be the main headline in the line-up should he be selected. Klopp has already confirmed that he is available, with the Brazil international likely to replace Gini Wijnaldum, who was anonymous at the weekend, in the first eleven.
For Sevilla, Johannes Geis, on loan from Schalke, is out injured, as is key man Nolito, who was signed from Manchester City during the summer after just one difficult season at the Etihad.
Los Rojiblancos are unbeaten so far this season, with a draw and two wins in La Liga. Manager Eduardo Berizzo, who took over from Jorge Sampaoli in the summer, who went to manage Argentina, has had a solid start so far, but this will be his sternest test.
Liverpool will be looking for revenge after losing the Europa League final to Sevilla in 2016, but in truth this is a very different side to the one which won three consecutive European finals. Kevin Gameiro, who scored against Liverpool in that final, has been lost to Atletico Madrid.
Jurgen Klopp’s pre-game press conference will take place at 7pm on Tuesday, just over 24 hours before the match kicks off.
WHEN DOES THE GAME KICK OFF?
The match starts at 19:45 BST on Wednesday and is live on BT Sport in the UK.
WHO IS THE REFEREE?
Danny Makkelie – the Dutch official has taken charge of three league games in Holland so far this season so far and also the Eredivisie equivalent of the Community Shield, where Feyenoord beat Vitesse Arnheim on penalties.
He has never refereed Liverpool or Sevilla before, but has officiated on English soil three times over the years, starting with Newcastle’s 1-1 draw with Maritimo in the Europa League in November 2012.
In the Champions League, he saw Chelsea beat Maribor, a team Liverpool will face later in the group stage, by six goals to nil in October 2014, and Manchester City’s 4-2 win over Borussia Monchengladbach in December 2015.
Former Sevilla man Alberto Moreno has already played more times this season than he did in the whole of last season, just six games in.
Liverpool: Karius; Gomez, Lovren, Matip, Robertson; Henderson, Coutinho, Can; Mane, Firmino, Salah
Sevilla: Rico; Mercado, Carrico, Lenglet, Escudero; Nzonzi; Navas, Sarabia, Ganso, Correa; Ben Yedder
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