Competition: Premier League Date: Sunday 27th November 2016 Venue: Old Trafford Kick-Off: 16:30 GMT
Manchester United remain without first-choice defenders Chris Smalling and Eric Bailly, meaning Phil Jones and Marcos Rojo will continue in the back-line.
Zlatan Ibrahimovic returns from suspension to lead the line, whilst Michael Carrick could be rested rather than playing his third match in a week.
West Ham welcome Mark Noble back from suspension but will have to cope without Winston Reid, who serves a suspension of his own.
Andy Carroll has returned to training and may make the Hammers squad, although a start is extremely unlikely.
After a crushing equaliser cost Manchester United all three points against Arsenal last week, the Red Devils need a victory tomorrow to keep pace with those ahead of them in the standings. On the back of a 4-0 victory over Feyenoord, Jose Mourinho’s best result in a year, the hosts will be full of confidence.
West Ham have struggled this season and will be looking over their shoulders this weekend. Their recent record over Manchester United is strong, including a 3-2 victory last season, but the Hammers have struggled to get a result at Old Trafford.
Expect West Ham’s search for an Old Trafford victory in the Premier League to continue and the Red Devils should have enough to secure all three points and extend their unbeaten run in the league to four matches.
De Gea, Valencia, Rojo, Jones, Shaw, Fellaini, Herrera, Mata, Pogba, Mkhitaryan, Ibrahimovic
Adrian, Collins, Kouyate, Ogbonna, Antonio, Noble, Obiang, Cresswell, Payet, Lanzini, Ayew
Manchester United have drawn their last three Premier League matches at Old Trafford.
West Ham have lost six of their last seven games on the road in the league.
United are undefeated in their last ten Premier League matches at home against West Ham.