Competition: Europa League Date: Thursday 20th October 2016 Venue: San Siro Kick-Off: 18:00 BST
Southampton defender Matt Targett remains a doubt for the trip to the San Siro on Thursday night, after suffering a hamstring injury in the win over Burnley at the weekend.
Manager Claude Puel is likely to rotate his squad ahead of the Europa League clash, with Shane Long, Pierre Hojbjerg and Maya Yoshida set for a return to the starting line-up, having been rested at the weekend.
As for Inter, they could hand recalls for forwards Eder and Rodrigo Palacio who have started the last two matches in Europe for the Nerazzurri.
On the injury front, defender Andrea Ranocchia is still sidelined for the hosts due to an Achilles injury, joining absentees Felipe Melo and Marco Andreolli.
Southampton look to continue their unbeaten start in the Europa League, when they face Italian giants Inter Milan at the San Siro on Thursday night.
The Saints head into the match following a commanding performance at the weekend, with a Charlie Austin double securing a 3-1 victory at St Mary’s, extending their run to six matches unbeaten in all competitions.
Claude Puel’s men top Group K after two games with a win and draw to their name, and furthermore are yet to concede a goal in Europe this season, after a 3-0 opening win over Sparta Prague and goalless draw away to Israeli side Hapoel Be’er Sheva a fortnight ago.
In contrast, Internazionale welcome their Premier League opponents, still searching for their first point in Europe, following back to back defeats to leave them bottom of the group.
Domestically, it tells a similar tale for the Nerazzurri who are winless in their last three league matches, after a demoralising 2-1 home loss to Cagliuri at the weekend which included a penalty miss by captain Mauro Icardi.
Head coach Frank Boer will be feeling the pressure a bit, and he knows a third straight loss for his side would surely put a dent in their European journey, and the heavy load will fall more on Inter to pick up a win on Thursday night.
To go on current form the Saints look the favourites to pick up at least point against an Inter side low in confidence, and I’m going for a both teams to score draw at the San Siro venue.
Handanovic (GK), D’Ambrosio, Ansaldi, Murillo, Miangue, Medel, Banega, Perisic, Candreva, Palacio, Eder
Forster (GK), Cedric, Fonte, Van Dijk, Yoshida, Ward-Prowse, Romeu, Davis, Hojbjerg, Austin, Long