Competition: La Liga Date: Sunday 21st August 2016 Venue: Anoeta Stadium Date: 19:15 BST
Real Sociedad forward Imanol Agirretxe will miss the opening home match of the season with a knee injury, along with defenders Raul Navas (hip) and Carlos Martinez (hamstring).
Eusebio Sacristan could hand debuts to Brazilian forward Willian Jose and former Southampton striker Juanmi on Sunday.
Meanwhile, the visitors welcome the return of striker Alvaro Morata, after re-signing him from Juventus for a fee around €30m.
However, Los Blancos have suffered a massive blow with Portuguese star Cristiano Ronaldo set to miss the La Liga opener due to a leg injury, alongside Pepe (thigh), Karim Benzema (hip) and Luka Modric who is out through suspension.
Real Madrid begin their first match of the 2016/17 La Liga campaign, when they travel to play Real Sociedad at the Anoeta Stadium on Sunday night.
Zinedine Zidane’s side narrowly missed out on the title last season finishing second behind rivals Barcelona, however, they’ll be going into the new campaign on a high after their UEFA Super Cup victory over Sevilla last week.
Also, Los Blancos will be looking to make it five straight league wins going into Sunday’s match, and are unbeaten in their last nine matches on the road.
As for the hosts, they look to make it three straight home wins in the league when they welcome the reigning European Champions to the Anoeta.
Last season, the Royals finished a respective 9th in the table and manager Eusebio Sacristan is hoping his side can go one further this season and qualify for the Europa League.
Real Sociedad’s last win over their weekend opponents came during the 2014/15 season, but since then they’ve suffered three straight losses to Madrid.
Rulli (GK), Elustondo, Gonzalez, Litri, Martinez, Ilarramendi, Pardo, Granero, Jose, Juanmi, Vela
Navas (GK), Cavarjal, Varane, Ramos, Marcelo, Isco, Casemiro, Kroos, Ascensio, Morata, Bale
Real Sociedad have won just one of their last 19 games against Real Madrid.
Real Madrid have won five of the last six meetings against Real Sociedad.